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Discovery of N-(2-Aminophenyl)-4-(bis(2-chloroethyl)amino)Benzamide as a Potent Histone Deacetylase Inhibitor

Inhibition of histone deacetylases (HDACs) has been an important emerging therapy for the treatment of multiple cancers. However, the application of HDAC inhibitors is restricted by the limited potency against solid tumors. In order to discover novel HDAC inhibitors with potent antitumor activities,...

पूर्ण विवरण

में बचाया:
ग्रंथसूची विवरण
में प्रकाशित:Front Pharmacol
मुख्य लेखकों: Zhang, Lihui, Li, Xiaoyang, Chen, Yiming, Wan, Minghui, Jiang, Qixiao, Zhang, Li, Chou, C. James, Song, Weiguo, Zhang, Lei
स्वरूप: Artigo
भाषा:Inglês
प्रकाशित: Frontiers Media S.A. 2019
विषय:
ऑनलाइन पहुंच:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730478/
https://ncbi.nlm.nih.gov/pubmed/31543818
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphar.2019.00957
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