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Discovery of indole-3-butyric acid derivatives as potent histone deacetylase inhibitors
In discovery of HDAC inhibitors (HDACIs) with improved anticancer potency, structural modification was performed on the previous derived indole-3-butyric acid derivative. Among all the synthesised compounds, molecule I13 exhibited high HDAC inhibitory and antiproliferative potencies in the in vitro...
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| Publicado no: | J Enzyme Inhib Med Chem |
|---|---|
| Main Authors: | , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Taylor & Francis
2021
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7822065/ https://ncbi.nlm.nih.gov/pubmed/33445997 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1080/14756366.2020.1870457 |
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