Brain-Derived Neurotrophic Factor Induces Mammalian Target of Rapamycin-Dependent Local Activation of Translation Machinery and Protein Synthesis in Neuronal Dendrites

In neurons, perisynaptic or dendritic translation is implicated in synapse-wide alterations of function and morphology triggered by neural activity. The molecular mechanisms controlling local translation activation, however, have yet to be elucidated. Here, we show that local protein synthesis and t...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Takei, Nobuyuki, Inamura, Naoko, Kawamura, Mihoko, Namba, Hisaaki, Hara, Kenta, Yonezawa, Kazuyoshi, Nawa, Hiroyuki
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2004
Subjects:
Cellular/Molecular
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6730227/
https://ncbi.nlm.nih.gov/pubmed/15525761
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1427-04.2004
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