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The c-Jun N-Terminal Protein Kinase Signaling Pathway Mediates Bax Activation and Subsequent Neuronal Apoptosis through Interaction with Bim after Transient Focal Cerebral Ischemia

The c-Jun N-terminal protein kinase (JNK) signaling pathway is implicated in neuronal apoptosis. The mechanism by which activated JNK induces neuronal apoptosis is strongly linked to mitochondrial apoptogenic proteins, although the molecular machinery downstream of JNK has not been precisely elucida...

詳細記述

保存先:
書誌詳細
出版年:J Neurosci
主要な著者: Okuno, Shuzo, Saito, Atsushi, Hayashi, Takeshi, Chan, Pak H.
フォーマット: Artigo
言語:Inglês
出版事項: Society for Neuroscience 2004
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729938/
https://ncbi.nlm.nih.gov/pubmed/15356200
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.1745-04.2004
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