Neuroprotective Effects of a Novel Inhibitor of c-Jun N-Terminal Kinase in the Rat Model of Transient Focal Cerebral Ischemia

A novel specific inhibitor of c-Jun N-terminal kinase, 11H-indeno[1,2-b]quinoxalin-11-one oxime sodium salt (IQ-1S), has a high affinity to JNK3 compared to JNK1/JNK2. The aim of this work was to study the mechanisms of neuroprotective activity of IQ-1S in the models of reversible focal cerebral isc...

Descrición completa

Gardado en:
Detalles Bibliográficos
Publicado en:Cells
Main Authors: Plotnikov, Mark B., Chernysheva, Galina A., Smolyakova, Vera I., Aliev, Oleg I., Trofimova, Eugene S., Sherstoboev, Eugene Y., Osipenko, Anton N., Khlebnikov, Andrei I., Anfinogenova, Yana J., Schepetkin, Igor A., Atochin, Dmitriy N.
Formato: Artigo
Idioma:Inglês
Publicado: MDPI 2020
Assuntos:
Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC7464312/
https://ncbi.nlm.nih.gov/pubmed/32784475
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3390/cells9081860
Tags: Engadir etiqueta
Sen Etiquetas, Sexa o primeiro en etiquetar este rexistro!

Títulos similares