Endogenous Activation of mGlu5 Metabotropic Glutamate Receptors Contributes to the Development of Nigro-Striatal Damage Induced by 1-Methyl-4-Phenyl-1,2,3,6-Tetrahydropyridine in Mice

We combined the use of knock-out mice and subtype-selective antagonists [2-methyl-6-(phenylethynyl)pyridine (MPEP) and (E)-2-methyl-6-(2-phenylethenyl)-pyridine (SIB1893)] to examine whether endogenous activation of mGlu5 metabotropic glutamate receptors contributes to the pathophysiology of nigro-s...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Battaglia, Giuseppe, Busceti, Carla L., Molinaro, Gemma, Biagioni, Francesca, Storto, Marianna, Fornai, Francesco, Nicoletti, Ferdinando, Bruno, Valeria
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2004
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729818/
https://ncbi.nlm.nih.gov/pubmed/14749427
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3831-03.2004
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