تحميل...
Neutralization of Transthyretin Reverses the Neuroprotective Effects of Secreted Amyloid Precursor Protein (APP) in APP(Sw) Mice Resulting in Tau Phosphorylation and Loss of Hippocampal Neurons: Support for the Amyloid Hypothesis
Alzheimer's disease (AD) may be caused by the abnormal processing of the amyloid precursor protein (APP) and the accumulation of β-amyloid (Aβ). The amyloid precursor protein can be proteolytically cleaved into multiple fragments, many of which have distinct biological actions. Although a high...
محفوظ في:
| الحاوية / القاعدة: | J Neurosci |
|---|---|
| المؤلفون الرئيسيون: | , , , , , |
| التنسيق: | Artigo |
| اللغة: | Inglês |
| منشور في: |
Society for Neuroscience
2004
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| الموضوعات: | |
| الوصول للمادة أونلاين: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6729623/ https://ncbi.nlm.nih.gov/pubmed/15342738 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2211-04.2004 |
| الوسوم: |
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