Defective Neuromuscular Synapses in Mice Lacking Amyloid Precursor Protein (APP) and APP-Like Protein 2

Biochemical and genetic studies place the amyloid precursor protein (APP) at the center stage of Alzheimer's disease (AD) pathogenesis. Although mutations in the APP gene lead to dominant inheritance of familial AD, the normal function of APP remains elusive. Here, we report that the APP family...

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Veröffentlicht in:J Neurosci
Hauptverfasser: Wang, Pei, Yang, Guang, Mosier, Dennis R., Chang, Paul, Zaidi, Tahire, Gong, Yan-Dao, Zhao, Nan-Ming, Dominguez, Bertha, Lee, Kuo-Fen, Gan, Wen-Biao, Zheng, Hui
Format: Artigo
Sprache:Inglês
Veröffentlicht: Society for Neuroscience 2005
Schlagworte:
Neurobiology of Disease
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725967/
https://ncbi.nlm.nih.gov/pubmed/15689559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4660-04.2005
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