Defective Neuromuscular Synapses in Mice Lacking Amyloid Precursor Protein (APP) and APP-Like Protein 2

Biochemical and genetic studies place the amyloid precursor protein (APP) at the center stage of Alzheimer's disease (AD) pathogenesis. Although mutations in the APP gene lead to dominant inheritance of familial AD, the normal function of APP remains elusive. Here, we report that the APP family...

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Detalhes bibliográficos
Publicado no:J Neurosci
Main Authors: Wang, Pei, Yang, Guang, Mosier, Dennis R., Chang, Paul, Zaidi, Tahire, Gong, Yan-Dao, Zhao, Nan-Ming, Dominguez, Bertha, Lee, Kuo-Fen, Gan, Wen-Biao, Zheng, Hui
Formato: Artigo
Idioma:Inglês
Publicado em: Society for Neuroscience 2005
Assuntos:
Neurobiology of Disease
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725967/
https://ncbi.nlm.nih.gov/pubmed/15689559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4660-04.2005
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