Defective Neuromuscular Synapses in Mice Lacking Amyloid Precursor Protein (APP) and APP-Like Protein 2

Biochemical and genetic studies place the amyloid precursor protein (APP) at the center stage of Alzheimer's disease (AD) pathogenesis. Although mutations in the APP gene lead to dominant inheritance of familial AD, the normal function of APP remains elusive. Here, we report that the APP family...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Wang, Pei, Yang, Guang, Mosier, Dennis R., Chang, Paul, Zaidi, Tahire, Gong, Yan-Dao, Zhao, Nan-Ming, Dominguez, Bertha, Lee, Kuo-Fen, Gan, Wen-Biao, Zheng, Hui
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2005
Materias:
Neurobiology of Disease
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725967/
https://ncbi.nlm.nih.gov/pubmed/15689559
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4660-04.2005
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