Neutralization of Transthyretin Reverses the Neuroprotective Effects of Secreted Amyloid Precursor Protein (APP) in APP(Sw) Mice Resulting in Tau Phosphorylation and Loss of Hippocampal Neurons: Support for the Amyloid Hypothesis

Lignende værker

• Soluble amyloid precursor protein (APP) regulates transthyretin and Klotho gene expression without rescuing the essential function of APP
  af: Li, Hongmei, et al.
  Udgivet: (2010)
• Phosphorylation of the amyloid precursor protein (APP) at Ser-675 promotes APP processing involving meprin β
  af: Menon, Preeti Kumaran, et al.
  Udgivet: (2019)
• Reconsideration of Amyloid Hypothesis and Tau Hypothesis in Alzheimer's Disease
  af: Kametani, Fuyuki, et al.
  Udgivet: (2018)
• Lack of Neurodegeneration in Transgenic Mice Overexpressing Mutant Amyloid Precursor Protein Is Associated with Increased Levels of Transthyretin and the Activation of Cell Survival Pathways
  af: Stein, Thor D., et al.
  Udgivet: (2002)
• Defective Neuromuscular Synapses in Mice Lacking Amyloid Precursor Protein (APP) and APP-Like Protein 2
  af: Wang, Pei, et al.
  Udgivet: (2005)