Age-Dependent Neurodegeneration and Alzheimer-Amyloid Plaque Formation in Transgenic Drosophila

β-Amyloid peptides that are cleaved from the amyloid precursor protein (APP) play a critical role in Alzheimer's disease (AD) pathophysiology. Here, we show that in Drosophila, the targeted expression of the key genes of AD, APP, theβ-site APP-cleaving enzyme BACE, and the presenilins led to th...

Descripció completa

Guardat en:
Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Greeve, Isabell, Kretzschmar, Doris, Tschäpe, Jakob-Andreas, Beyn, Anika, Brellinger, Claire, Schweizer, Michaela, Nitsch, Roger M., Reifegerste, Rita
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2004
Matèries:
Neurobiology of Disease
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729409/
https://ncbi.nlm.nih.gov/pubmed/15102905
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0283-04.2004
Etiquetes: Afegir etiqueta
Sense etiquetes, Sigues el primer a etiquetar aquest registre!

Ítems similars