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Neurotoxic effects induced by the Drosophila amyloid-β peptide suggest a conserved toxic function
The accumulation of amyloid-β (Aβ) into plaques is a hallmark feature of Alzheimer's disease (AD). While amyloid precursor protein (APP)-related proteins are found in most organisms, only Aβ fragments from human APP have been shown to induce amyloid deposits and progressive neurodegeneration. T...
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| Pubblicato in: | Neurobiol Dis |
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| Autori principali: | , , , , , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2008
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4418460/ https://ncbi.nlm.nih.gov/pubmed/19049874 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.nbd.2008.10.014 |
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