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Drosophila Full-Length Amyloid Precursor Protein is Required for Visual Working Memory and Prevents Age-Related Memory Impairment
The β-amyloid precursor protein (APP) plays a central role in the etiology of Alzheimer’s disease (AD). However, its normal physiological functions are still unclear. APP is cleaved by various secretases whereby sequential processing by the β- and γ-secretases produces the β-amyloid peptide that is...
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| Yayımlandı: | Curr Biol |
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| Asıl Yazarlar: | , , , , |
| Materyal Türü: | Artigo |
| Dil: | Inglês |
| Baskı/Yayın Bilgisi: |
2018
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| Konular: | |
| Online Erişim: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5840017/ https://ncbi.nlm.nih.gov/pubmed/29478851 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.cub.2018.01.077 |
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