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Single-Channel Analysis of KCNQ K(+) Channels Reveals the Mechanism of Augmentation by a Cysteine-Modifying Reagent
The cysteine-modifying reagent N-ethylmaleimide (NEM) is known to augment currents from native M-channels in sympathetic neurons and cloned KCNQ2 channels. As a probe for channel function, we investigated the mechanism of NEM action and subunit specificity of cloned KCNQ2–5 channels expressed in Chi...
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| Vydáno v: | J Neurosci |
|---|---|
| Hlavní autoři: | , , |
| Médium: | Artigo |
| Jazyk: | Inglês |
| Vydáno: |
Society for Neuroscience
2004
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| Témata: | |
| On-line přístup: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6729199/ https://ncbi.nlm.nih.gov/pubmed/15175377 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.0882-04.2004 |
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