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Antibodies and a cysteine-modifying reagent show correspondence of M current in neurons to KCNQ2 and KCNQ3 K(+) channels

1. KCNQ K(+) channels are thought to underlie the M current of neurons. To probe if the KCNQ2 and KCNQ3 subtypes underlie the M current of rat superior cervical ganglia (SCG) neurons and of hippocampus, we raised specific antibodies against them and also used the cysteine-alkylating agent N-ethylmal...

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Detalhes bibliográficos
Main Authors: Roche, John P, Westenbroek, Ruth, Sorom, Abraham J, Hille, Bertil, Mackie, Ken, Shapiro, Mark S
Formato: Artigo
Idioma:Inglês
Publicado em: 2002
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1573614/
https://ncbi.nlm.nih.gov/pubmed/12466226
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/sj.bjp.0704989
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