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Reconstitution of Muscarinic Modulation of the KCNQ2/KCNQ3 K(+) Channels That Underlie the Neuronal M Current

Channels from KCNQ2 and KCNQ3 genes have been suggested to underlie the neuronal M-type K(+) current. The M current is modulated by muscarinic agonists via G-proteins and an unidentified diffusible cytoplasmic messenger. Using whole-cell clamp, we studied tsA-201 cells in which cloned KCNQ2/KCNQ3 ch...

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Vydáno v:J Neurosci
Hlavní autoři: Shapiro, Mark S., Roche, John P., Kaftan, Edward J., Cruzblanca, Humberto, Mackie, Ken, Hille, Bertil
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2000
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On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6772928/
https://ncbi.nlm.nih.gov/pubmed/10684873
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.20-05-01710.2000
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