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Structural Requirements for Differential Sensitivity of KCNQ K(+) Channels to Modulation by Ca(2)+/Calmodulin

Calmodulin modulation of ion channels has emerged as a prominent theme in biology. The sensitivity of KCNQ1–5 K(+) channels to modulation by Ca(2+)/calmodulin (CaM) was studied using patch-clamp, Ca(2+) imaging, and biochemical and pharmacological approaches. Coexpression of CaM in Chinese hamster o...

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Detalhes bibliográficos
Main Authors: Gamper, Nikita, Li, Yang, Shapiro, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2005
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1182296/
https://ncbi.nlm.nih.gov/pubmed/15901836
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E04-09-0849
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