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Calmodulin Mediates Ca(2+)-dependent Modulation of M-type K(+) Channels

To quantify the modulation of KCNQ2/3 current by [Ca(2+)](i) and to test if calmodulin (CaM) mediates this action, simultaneous whole-cell recording and Ca(2+) imaging was performed on CHO cells expressing KCNQ2/3 channels, either alone, or together with wild-type (wt) CaM, or dominant-negative (DN)...

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Detalhes bibliográficos
Main Authors: Gamper, Nikita, Shapiro, Mark S.
Formato: Artigo
Idioma:Inglês
Publicado em: The Rockefeller University Press 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2234471/
https://ncbi.nlm.nih.gov/pubmed/12810850
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200208783
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