Angiotensin II regulates neuronal excitability via phosphatidylinositol 4,5-bisphosphate-dependent modulation of Kv7 (M-type) K(+) channels

Voltage-gated Kv7 (KCNQ) channels underlie important K(+) currents in many different types of cells, including the neuronal M current, which is thought to be modulated by muscarinic stimulation via depletion of membrane phosphatidylinositol 4,5-bisphosphate (PIP(2)). We studied the role of modulatio...

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Detalhes bibliográficos
Main Authors: Zaika, Oleg, Lara, Lucienne S, Gamper, Nikita, Hilgemann, Donald W, Jaffe, David B, Shapiro, Mark S
Formato: Artigo
Idioma:Inglês
Publicado em: Blackwell Science Inc 2006
Assuntos:
Cellular
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1819424/
https://ncbi.nlm.nih.gov/pubmed/16777936
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1113/jphysiol.2006.114074
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