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A Carboxy-terminal Inter-Helix Linker As the Site of Phosphatidylinositol 4,5-Bisphosphate Action on Kv7 (M-type) K(+) Channels

The regulation of M-type (KCNQ [Kv7]) K(+) channels by phosphatidylinositol 4,5-bisphosphate (PIP(2)) has perhaps the best correspondence to physiological signaling, but the site of action and structural motif of PIP(2) on these channels have not been established. Using single-channel recordings of...

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Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Hernandez, Ciria C., Zaika, Oleg, Shapiro, Mark S.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: The Rockefeller University Press 2008
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC2518730/
https://ncbi.nlm.nih.gov/pubmed/18725531
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1085/jgp.200810007
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