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Phosphatidylinositol 4,5-bisphosphate (PIP(2)) regulates KCNQ3 K(+) channels by interacting with four cytoplasmic channel domains

Phosphatidylinositol 4,5-bisphosphate (PIP(2)) in the plasma membrane regulates the function of many ion channels, including M-type (potassium voltage-gated channel subfamily Q member (KCNQ), K(v)7) K(+) channels; however, the molecular mechanisms involved remain unclear. To this end, we here focuse...

Täydet tiedot

Tallennettuna:
Bibliografiset tiedot
Julkaisussa:J Biol Chem
Päätekijät: Choveau, Frank S., De la Rosa, Victor, Bierbower, Sonya M., Hernandez, Ciria C., Shapiro, Mark S.
Aineistotyyppi: Artigo
Kieli:Inglês
Julkaistu: American Society for Biochemistry and Molecular Biology 2018
Aiheet:
Linkit:https://ncbi.nlm.nih.gov/pmc/articles/PMC6302169/
https://ncbi.nlm.nih.gov/pubmed/30348901
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.RA118.005401
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