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Small molecule target identification using photo-affinity chromatography

Identification of the protein targets of bioactive small molecules is a routine challenge in chemical biology and phenotype-based drug discovery. Recent years have seen an explosion of approaches to meeting this challenge, but the traditional method of affinity pulldowns remains a practical choice i...

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Bibliografiske detaljer
Udgivet i:Methods Enzymol
Main Authors: Seo, Seung-Yong, Corson, Timothy W.
Format: Artigo
Sprog:Inglês
Udgivet: 2019
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729133/
https://ncbi.nlm.nih.gov/pubmed/31155061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.02.028
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