Drug Affinity Responsive Target Stability (DARTS) for Small Molecule Target Identification

Drug Affinity Responsive Target Stability (DARTS) is a relatively quick and straightforward approach to identify potential protein targets for small molecules. It relies on the protection against proteolysis conferred on the target protein by interaction with a small molecule. The greatest advantage...

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Detalhes bibliográficos
Publicado no:Methods Mol Biol
Main Authors: Pai, Melody Y., Lomenick, Brett, Hwang, Heejun, Schiestl, Robert, McBride, William, Loo, Joseph A., Huang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2015
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4442491/
https://ncbi.nlm.nih.gov/pubmed/25618353
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/978-1-4939-2269-7_22
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