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Target identification using drug affinity responsive target stability (DARTS)

Drug Affinity Responsive Target Stability is a general methodology for identifying and studying protein-ligand interactions. The technique is based on the principle that when a small molecule compound binds to a protein, the interaction stabilizes the target protein’s structure such that it becomes...

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Detalhes bibliográficos
Main Authors: Lomenick, Brett, Jung, Gwanghyun, Wohlschlegel, James A., Huang, Jing
Formato: Artigo
Idioma:Inglês
Publicado em: 2011
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3251962/
https://ncbi.nlm.nih.gov/pubmed/22229126
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470559277.ch110180
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