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Target identification using drug affinity responsive target stability (DARTS)
Drug Affinity Responsive Target Stability is a general methodology for identifying and studying protein-ligand interactions. The technique is based on the principle that when a small molecule compound binds to a protein, the interaction stabilizes the target protein’s structure such that it becomes...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
2011
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3251962/ https://ncbi.nlm.nih.gov/pubmed/22229126 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/9780470559277.ch110180 |
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