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Small molecule target identification using photo-affinity chromatography

Identification of the protein targets of bioactive small molecules is a routine challenge in chemical biology and phenotype-based drug discovery. Recent years have seen an explosion of approaches to meeting this challenge, but the traditional method of affinity pulldowns remains a practical choice i...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Cyhoeddwyd yn:Methods Enzymol
Prif Awduron: Seo, Seung-Yong, Corson, Timothy W.
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: 2019
Pynciau:
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC6729133/
https://ncbi.nlm.nih.gov/pubmed/31155061
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/bs.mie.2019.02.028
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