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Binding affinity and kinetic analysis of targeted small molecule-modified nanoparticles

Nanoparticles bearing surface-conjugated targeting ligands are increasingly being explored for a variety of biomedical applications. The multivalent conjugation of targeting ligands on the surface of nanoparticles is presumed to enhance binding to the desired target. However, given the complexities...

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Autors principals: Tassa, Carlos, Duffner, Jay L., Lewis, Timothy A., Weissleder, Ralph, Schreiber, Stuart L., Koehler, Angela N., Shaw, Stanley Y.
Format: Artigo
Idioma:Inglês
Publicat: 2010
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC2902264/
https://ncbi.nlm.nih.gov/pubmed/20028085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bc900438a
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