The Nrf2 activator RTA-408 attenuates osteoclastogenesis by inhibiting STING dependent NF-κb signaling

The dysregulation of ROS production and osteoclastogenesis is involved in the progress of osteoporosis. To identify novel and effective targets to treat this disease, it is important to explore the underlying mechanisms. In our study, we firstly tested the effect of the Nrf2 activator RTA-408, a nov...

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發表在:Redox Biol
Main Authors: Sun, Xuewu, Xie, Ziang, Hu, Bin, Zhang, Boya, Ma, Yan, Pan, Xin, Huang, Hai, Wang, Jiying, Zhao, Xiangde, Jie, Zhiwei, Shi, Peihua, Chen, Zhijun
格式: Artigo
語言:Inglês
出版: Elsevier 2019
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Research Paper
在線閱讀:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728880/
https://ncbi.nlm.nih.gov/pubmed/31487581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101309
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