The Nrf2 activator RTA-408 attenuates osteoclastogenesis by inhibiting STING dependent NF-κb signaling

The dysregulation of ROS production and osteoclastogenesis is involved in the progress of osteoporosis. To identify novel and effective targets to treat this disease, it is important to explore the underlying mechanisms. In our study, we firstly tested the effect of the Nrf2 activator RTA-408, a nov...

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Detalhes bibliográficos
Publicado no:Redox Biol
Main Authors: Sun, Xuewu, Xie, Ziang, Hu, Bin, Zhang, Boya, Ma, Yan, Pan, Xin, Huang, Hai, Wang, Jiying, Zhao, Xiangde, Jie, Zhiwei, Shi, Peihua, Chen, Zhijun
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2019
Assuntos:
Research Paper
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728880/
https://ncbi.nlm.nih.gov/pubmed/31487581
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.redox.2019.101309
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