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TAZ inhibits osteoclastogenesis by attenuating TAK1/NF-κB signaling

Osteoporosis is an osteolytic disorder commonly associated with excessive osteoclast formation. Transcriptional coactivator with PDZ-binding motif (TAZ) is a key downstream effector of the Hippo signaling pathway; it was suggested to be involved in the regulation of bone homeostasis. However, the ex...

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Bibliographic Details
Published in:Bone Res
Main Authors: Yang, Wanlei, Lu, Xuanyuan, Zhang, Tan, Han, Weiqi, Li, Jianlei, He, Wei, Jia, Yewei, Zhao, Kangxian, Qin, An, Qian, Yu
Format: Artigo
Language:Inglês
Published: Nature Publishing Group UK 2021
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC8275679/
https://ncbi.nlm.nih.gov/pubmed/34253712
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41413-021-00151-3
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