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Sex-specific Mendelian randomization study of genetically predicted insulin and cardiovascular events in the UK Biobank

Insulin drives growth and reproduction which trade-off against longevity. Genetically predicted insulin, i.e., insulin proxied by genetic variants, is positively associated with ischemic heart disease, but sex differences are unclear, despite different disease rates and reproductive strategies by se...

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Podrobná bibliografie
Vydáno v:Commun Biol
Hlavní autoři: Zhao, Jie V., Luo, Shan, Schooling, C. Mary
Médium: Artigo
Jazyk:Inglês
Vydáno: Nature Publishing Group UK 2019
Témata:
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728387/
https://ncbi.nlm.nih.gov/pubmed/31508506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0579-z
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