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Sex-specific Mendelian randomization study of genetically predicted insulin and cardiovascular events in the UK Biobank

Insulin drives growth and reproduction which trade-off against longevity. Genetically predicted insulin, i.e., insulin proxied by genetic variants, is positively associated with ischemic heart disease, but sex differences are unclear, despite different disease rates and reproductive strategies by se...

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Bibliografiska uppgifter
I publikationen:Commun Biol
Huvudupphovsmän: Zhao, Jie V., Luo, Shan, Schooling, C. Mary
Materialtyp: Artigo
Språk:Inglês
Publicerad: Nature Publishing Group UK 2019
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728387/
https://ncbi.nlm.nih.gov/pubmed/31508506
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s42003-019-0579-z
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