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Sex-specific Associations of Sex Hormone Binding Globulin with CKD and Kidney Function: A Univariable and Multivariable Mendelian Randomization Study in the UK Biobank

BACKGROUND: Kidney function declines faster in men. Testosterone levels may mediate the sex disparity. Correspondingly, levels of sex hormone binding globulin (SHBG), which modulates sex hormones, might also be relevant to the lower kidney function in men. The sex-specific role of SHBG is unclear. M...

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Shranjeno v:
Bibliografske podrobnosti
izdano v:J Am Soc Nephrol
Main Authors: Zhao, Jie V., Schooling, C. Mary
Format: Artigo
Jezik:Inglês
Izdano: American Society of Nephrology 2021
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920164/
https://ncbi.nlm.nih.gov/pubmed/33318152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020050659
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