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Sex-specific Associations of Sex Hormone Binding Globulin with CKD and Kidney Function: A Univariable and Multivariable Mendelian Randomization Study in the UK Biobank

BACKGROUND: Kidney function declines faster in men. Testosterone levels may mediate the sex disparity. Correspondingly, levels of sex hormone binding globulin (SHBG), which modulates sex hormones, might also be relevant to the lower kidney function in men. The sex-specific role of SHBG is unclear. M...

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Detalhes bibliográficos
Publicado no:J Am Soc Nephrol
Main Authors: Zhao, Jie V., Schooling, C. Mary
Formato: Artigo
Idioma:Inglês
Publicado em: American Society of Nephrology 2021
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC7920164/
https://ncbi.nlm.nih.gov/pubmed/33318152
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1681/ASN.2020050659
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