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Exploiting BBB Disruption for the Delivery of Nanocarriers to the Diseased CNS: Using BBB Disruption to Deliver Nanocarriers

The blood brain barrier (BBB) segregates the central nervous system from the systemic circulation. As such, the BBB prevents toxins and pathogens from entering the brain, but also limits the brain uptake of therapeutic molecules. However, under certain pathological conditions, the BBB is disrupted,...

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Detalles Bibliográficos
Publicado en:Curr Opin Biotechnol
Main Authors: Umlauf, Benjamin J., Shusta, Eric V.
Formato: Artigo
Idioma:Inglês
Publicado: 2019
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728237/
https://ncbi.nlm.nih.gov/pubmed/30849699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2019.01.013
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