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Exploiting BBB Disruption for the Delivery of Nanocarriers to the Diseased CNS: Using BBB Disruption to Deliver Nanocarriers
The blood brain barrier (BBB) segregates the central nervous system from the systemic circulation. As such, the BBB prevents toxins and pathogens from entering the brain, but also limits the brain uptake of therapeutic molecules. However, under certain pathological conditions, the BBB is disrupted,...
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| Pubblicato in: | Curr Opin Biotechnol |
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| Autori principali: | , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
2019
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6728237/ https://ncbi.nlm.nih.gov/pubmed/30849699 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2019.01.013 |
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