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Exploiting BBB Disruption for the Delivery of Nanocarriers to the Diseased CNS: Using BBB Disruption to Deliver Nanocarriers

The blood brain barrier (BBB) segregates the central nervous system from the systemic circulation. As such, the BBB prevents toxins and pathogens from entering the brain, but also limits the brain uptake of therapeutic molecules. However, under certain pathological conditions, the BBB is disrupted,...

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Bibliografische gegevens
Gepubliceerd in:Curr Opin Biotechnol
Hoofdauteurs: Umlauf, Benjamin J., Shusta, Eric V.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2019
Onderwerpen:
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6728237/
https://ncbi.nlm.nih.gov/pubmed/30849699
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.copbio.2019.01.013
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