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Mitochondrial translocation of cyclin C stimulates intrinsic apoptosis through Bax recruitment
Intrinsic apoptosis requires mitochondrial outer membrane disruption triggered by recruitment, activation, and oligomerization of the Bcl‐2 homology protein Bax. Following oxidative stress, we demonstrated that the transcriptional regulator cyclin C is released into the cytosol where it directs mito...
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| Udgivet i: | EMBO Rep |
|---|---|
| Main Authors: | , , , |
| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
John Wiley and Sons Inc.
2019
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6726902/ https://ncbi.nlm.nih.gov/pubmed/31385392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847425 |
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