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Mitochondrial translocation of cyclin C stimulates intrinsic apoptosis through Bax recruitment
Intrinsic apoptosis requires mitochondrial outer membrane disruption triggered by recruitment, activation, and oligomerization of the Bcl‐2 homology protein Bax. Following oxidative stress, we demonstrated that the transcriptional regulator cyclin C is released into the cytosol where it directs mito...
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| Publicado no: | EMBO Rep |
|---|---|
| Main Authors: | , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
John Wiley and Sons Inc.
2019
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6726902/ https://ncbi.nlm.nih.gov/pubmed/31385392 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.15252/embr.201847425 |
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