Vinculin and metavinculin exhibit distinct effects on focal adhesion properties, cell migration, and mechanotransduction

Vinculin (Vcn) is a ubiquitously expressed cytoskeletal protein that links transmembrane receptors to actin filaments, and plays a key role in regulating cell adhesion, motility, and force transmission. Metavinculin (MVcn) is a Vcn splice isoform that contains an additional exon encoding a 68-residu...

Celý popis

Uloženo v:
Podrobná bibliografie
Vydáno v:PLoS One
Hlavní autoři: Lee, Hyunna T., Sharek, Lisa, O’Brien, E. Timothy, Urbina, Fabio L., Gupton, Stephanie L., Superfine, Richard, Burridge, Keith, Campbell, Sharon L.
Médium: Artigo
Jazyk:Inglês
Vydáno: Public Library of Science 2019
Témata:
Research Article
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726196/
https://ncbi.nlm.nih.gov/pubmed/31483833
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0221962
Tagy: Přidat tag
Žádné tagy, Buďte první, kdo otaguje tento záznam!

Podobné jednotky