Identification of a new actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties

Vinculin, a cytoskeletal scaffold protein essential for embryogenesis and cardiovascular function, localizes to focal adhesions and adherens junctions, connecting cell surface receptors to the actin cytoskeleton. While vinculin interacts with many adhesion proteins, its interaction with filamentous...

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Main Authors: Thompson, Peter M., Tolbert, Caitlin E., Shen, Kai, Kota, Pradeep, Palmer, Sean M., Plevock, Karen M., Orlova, Albina, Galkin, Vitold E., Burridge, Keith, Egelman, Edward H., Dokholyan, Nikolay V., Superfine, Richard, Campbell, Sharon L.
Formato: Artigo
Idioma:Inglês
Publicado: 2014
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Article
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039106/
https://ncbi.nlm.nih.gov/pubmed/24685146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.03.002
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