Identification of a new actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties

Vinculin, a cytoskeletal scaffold protein essential for embryogenesis and cardiovascular function, localizes to focal adhesions and adherens junctions, connecting cell surface receptors to the actin cytoskeleton. While vinculin interacts with many adhesion proteins, its interaction with filamentous...

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Bibliografische gegevens
Hoofdauteurs: Thompson, Peter M., Tolbert, Caitlin E., Shen, Kai, Kota, Pradeep, Palmer, Sean M., Plevock, Karen M., Orlova, Albina, Galkin, Vitold E., Burridge, Keith, Egelman, Edward H., Dokholyan, Nikolay V., Superfine, Richard, Campbell, Sharon L.
Formaat: Artigo
Taal:Inglês
Gepubliceerd in: 2014
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Article
Online toegang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039106/
https://ncbi.nlm.nih.gov/pubmed/24685146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.03.002
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