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Identification of a new actin binding surface on vinculin that mediates mechanical cell and focal adhesion properties

Vinculin, a cytoskeletal scaffold protein essential for embryogenesis and cardiovascular function, localizes to focal adhesions and adherens junctions, connecting cell surface receptors to the actin cytoskeleton. While vinculin interacts with many adhesion proteins, its interaction with filamentous...

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Bibliografski detalji
Glavni autori: Thompson, Peter M., Tolbert, Caitlin E., Shen, Kai, Kota, Pradeep, Palmer, Sean M., Plevock, Karen M., Orlova, Albina, Galkin, Vitold E., Burridge, Keith, Egelman, Edward H., Dokholyan, Nikolay V., Superfine, Richard, Campbell, Sharon L.
Format: Artigo
Jezik:Inglês
Izdano: 2014
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC4039106/
https://ncbi.nlm.nih.gov/pubmed/24685146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2014.03.002
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