The structural basis of actin organization by vinculin and metavinculin

Vinculin is an essential adhesion protein that links membrane-bound integrin and cadherin receptors through their intracellular binding partners to filamentous actin, facilitating mechanotransduction. Here we present an 8.5 Å resolution cryo-EM reconstruction and pseudo-atomic model of the vinculin...

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Bibliographic Details
Published in:J Mol Biol
Main Authors: Kim, Laura Y., Thompson, Peter M., Lee, Hyunna T., Pershad, Mihir, Campbell, Sharon L., Alushin, Gregory M.
Format: Artigo
Language:Inglês
Published: 2015
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Article
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4738167/
https://ncbi.nlm.nih.gov/pubmed/26493222
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.09.031
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