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The structural basis of actin organization by vinculin and metavinculin
Vinculin is an essential adhesion protein that links membrane-bound integrin and cadherin receptors through their intracellular binding partners to filamentous actin, facilitating mechanotransduction. Here we present an 8.5 Å resolution cryo-EM reconstruction and pseudo-atomic model of the vinculin...
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| Publicado no: | J Mol Biol |
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| Main Authors: | , , , , , |
| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2015
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4738167/ https://ncbi.nlm.nih.gov/pubmed/26493222 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.09.031 |
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