Metavinculin tunes the flexibility and the architecture of vinculin induced bundles of actin filaments

Vinculin is an abundant protein found at cell-cell and cell-extracellular matrix junctions. In muscles, a longer splice-isoform of vinculin, metavinculin, is also expressed. The metavinculin-specific insert is part of the C-terminal tail domain, the actin-binding site of both isoforms. Mutations in...

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Bibliografiske detaljer
Udgivet i:J Mol Biol
Main Authors: Durer, Zeynep A. Oztug, McGillivary, Rebecca M., Kang, Hyeran, Elam, W. Austin, Vizcarra, Christina L., Hanein, Dorit, De La Cruz, Enrique M., Reisler, Emil, Quinlan, Margot E.
Format: Artigo
Sprog:Inglês
Udgivet: 2015
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC4540644/
https://ncbi.nlm.nih.gov/pubmed/26168869
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jmb.2015.07.005
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