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A structural model for vinculin insertion into PIP(2)-containing membranes and the effect of insertion on vinculin activation and localization
Vinculin, a scaffolding protein that localizes to focal adhesions (FA) and adherens junctions, links the actin cytoskeleton to the adhesive super-structure. While vinculin binds to a number of cytoskeletal proteins, it can also associate with phosphatidylinositol 4,5-bisphosphate (PIP(2)) to drive m...
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| 發表在: | Structure |
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| Main Authors: | , , , , , , , , |
| 格式: | Artigo |
| 語言: | Inglês |
| 出版: |
2017
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| 主題: | |
| 在線閱讀: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5299030/ https://ncbi.nlm.nih.gov/pubmed/28089450 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.str.2016.12.002 |
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