Cytoprotective Effects of Geranylgeranylacetone against Retinal Photooxidative Damage

Exposure to excessive light induces retinal photoreceptor cell damage, leading to development and progression of various retinal diseases. We tested the effect of geranylgeranylacetone (GGA), an acyclic polyisoprenoid, on light-induced retinal damage in mice. Oral treatment with GGA (1.0 mg/d) for 5...

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Detalles Bibliográficos
Publicado en:J Neurosci
Autores principales: Tanito, Masaki, Kwon, Yong-Won, Kondo, Norihiko, Bai, Jie, Masutani, Hiroshi, Nakamura, Hajime, Fujii, Junichi, Ohira, Akihiro, Yodoi, Junji
Formato: Artigo
Lenguaje:Inglês
Publicado: Society for Neuroscience 2005
Materias:
Development/Plasticity/Repair
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726103/
https://ncbi.nlm.nih.gov/pubmed/15745966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4866-04.2005
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