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Cytoprotective Effects of Geranylgeranylacetone against Retinal Photooxidative Damage

Exposure to excessive light induces retinal photoreceptor cell damage, leading to development and progression of various retinal diseases. We tested the effect of geranylgeranylacetone (GGA), an acyclic polyisoprenoid, on light-induced retinal damage in mice. Oral treatment with GGA (1.0 mg/d) for 5...

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Bibliographic Details
Published in:J Neurosci
Main Authors: Tanito, Masaki, Kwon, Yong-Won, Kondo, Norihiko, Bai, Jie, Masutani, Hiroshi, Nakamura, Hajime, Fujii, Junichi, Ohira, Akihiro, Yodoi, Junji
Format: Artigo
Language:Inglês
Published: Society for Neuroscience 2005
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726103/
https://ncbi.nlm.nih.gov/pubmed/15745966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4866-04.2005
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