Cytoprotective Effects of Geranylgeranylacetone against Retinal Photooxidative Damage

Exposure to excessive light induces retinal photoreceptor cell damage, leading to development and progression of various retinal diseases. We tested the effect of geranylgeranylacetone (GGA), an acyclic polyisoprenoid, on light-induced retinal damage in mice. Oral treatment with GGA (1.0 mg/d) for 5...

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Vydáno v:J Neurosci
Hlavní autoři: Tanito, Masaki, Kwon, Yong-Won, Kondo, Norihiko, Bai, Jie, Masutani, Hiroshi, Nakamura, Hajime, Fujii, Junichi, Ohira, Akihiro, Yodoi, Junji
Médium: Artigo
Jazyk:Inglês
Vydáno: Society for Neuroscience 2005
Témata:
Development/Plasticity/Repair
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726103/
https://ncbi.nlm.nih.gov/pubmed/15745966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4866-04.2005
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