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Cytoprotective Effects of Geranylgeranylacetone against Retinal Photooxidative Damage

Exposure to excessive light induces retinal photoreceptor cell damage, leading to development and progression of various retinal diseases. We tested the effect of geranylgeranylacetone (GGA), an acyclic polyisoprenoid, on light-induced retinal damage in mice. Oral treatment with GGA (1.0 mg/d) for 5...

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Bibliografske podrobnosti
izdano v:J Neurosci
Main Authors: Tanito, Masaki, Kwon, Yong-Won, Kondo, Norihiko, Bai, Jie, Masutani, Hiroshi, Nakamura, Hajime, Fujii, Junichi, Ohira, Akihiro, Yodoi, Junji
Format: Artigo
Jezik:Inglês
Izdano: Society for Neuroscience 2005
Teme:
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC6726103/
https://ncbi.nlm.nih.gov/pubmed/15745966
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4866-04.2005
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