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Transgenic Expression of Human Connexin32 in Myelinating Schwann Cells Prevents Demyelination in Connexin32-Null Mice

Mutations in Gap Junction β1 (GJB1), the gene encoding the gap junction protein connexin32 (Cx32), cause the X-linked form of Charcot-Marie-Tooth disease (CMT1X), an inherited demyelinating neuropathy. We investigated the possibility that the expression of mutant Cx32 in other cells besides myelinat...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Scherer, Steven S., Xu, Yi-Tian, Messing, Albee, Willecke, Klaus, Fischbeck, Kenneth H., Jeng, Linda Jo Bone
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2005
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725992/
https://ncbi.nlm.nih.gov/pubmed/15703409
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3082-04.2005
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