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Presenilin Attenuates Receptor-Mediated Signaling and Synaptic Function

Presenilin (PS) plays an essential role in intramembranous γ-secretase processing of amyloid precursor protein (APP) and several membrane-bound proteins. Here we report that selective accumulation of a membrane-tethered deleted in colorectal cancer (DCC) derivative (DCC-α) correlates with extensive...

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Dades bibliogràfiques
Publicat a:J Neurosci
Autors principals: Parent, Angèle T., Barnes, Natalie Y., Taniguchi, Yoshihito, Thinakaran, Gopal, Sisodia, Sangram S.
Format: Artigo
Idioma:Inglês
Publicat: Society for Neuroscience 2005
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6725985/
https://ncbi.nlm.nih.gov/pubmed/15703408
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.3850-04.2005
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