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β-Amyloid-Induced Neuronal Apoptosis Involves c-Jun N-Terminal Kinase-Dependent Downregulation of Bcl-w
β-Amyloid protein (Aβ) has been implicated as a key molecule in the neurodegenerative cascades of Alzheimer's disease (AD). Aβ directly induces neuronal apoptosis, suggesting an important role of Aβ neurotoxicity in AD neurodegeneration. However, the mechanism(s) of Aβ-induced neuronal apoptosi...
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| Pubblicato in: | J Neurosci |
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| Autori principali: | , , |
| Natura: | Artigo |
| Lingua: | Inglês |
| Pubblicazione: |
Society for Neuroscience
2005
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| Soggetti: | |
| Accesso online: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6725978/ https://ncbi.nlm.nih.gov/pubmed/15689551 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.4736-04.2005 |
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