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Estrogen Regulates Bcl-w and Bim Expression: Role in Protection against β-Amyloid Peptide-Induced Neuronal Death

Estrogen is neuroprotective against a variety of insults, including β-amyloid peptide (Aβ); however, the underlying mechanism(s) is not fully understood. Here, we report that 17β-estradiol (E2) selectively regulates neuronal expression of the Bcl-2 family (bcl-2, bcl-x, bcl-w, bax, bak, bad, bik, bn...

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Détails bibliographiques
Publié dans:J Neurosci
Auteurs principaux: Yao, Mingzhong, Nguyen, Thuy-Vi V., Pike, Christian J.
Format: Artigo
Langue:Inglês
Publié: Society for Neuroscience 2007
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC6673600/
https://ncbi.nlm.nih.gov/pubmed/17287517
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1523/JNEUROSCI.2382-06.2007
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